“The Third family of Sant”.
All Corrections/Additions are Welcome
New page: 11-11-2026;
Our data online is to share. We do appreciate if you find a connection to share your data, so it can help many others all across this planet. Note: Not all descendants are listed. |
Corsair Nicola de Sayd had several illegitimate children from his Ethiopian Slave. All children and their mother were granted freedom, upon Nicola’s death. They were set up in Ghurgur, Malta. Nicola Santu, the illegitimate son of Don Nicola Sayd and an Ethiopian slave. The surname of Santu comes from Santi, the residence where Don Nicola Sayd had resided amongst other places. Nicola Santu was granted freedom along with his mother and siblings, and later became an Arbitant in Casal Lia and resided in Ghargur, Malta. The founder of the Name-sake Sant and the ancestor of the Counts Sant and Fournier and ancestor of much of the nobility in Malta.
References: Notary Vincenzo Cagega, 29th of December 1536.”Manumission of slave”[link]: The Noble Nicola Sayd gave liberty upon his death to one of his slaves and her children, who took the name of “Antonia Santu” upon Baptism. With their freedom, a house in Ghargur was provided and 2 turmi of land in that district. Antonia was purchased about 1530 amongst other slaves of Ethiopian abstract. It was quite common for this period when slavery was released to either take their master’s surname, a sponsor, or the town where one spent. Thus the surname of Sant (Sanctu, Santu) had come from. Interesting enough, most Maltese today can locate either a Slave, or an illegitimate ancestor. This is yet another one of those where a family worked its way to the riches of Nobility. Hopefully in the near future, a profile of Antonia Sanctu will be provided. So far, I only know that she was of Ethiopian descent. Perhaps even of Imperial blood. One will never know exactly, as the Imperial House of Soloman in Ethiopia was quite unstable at the beginning of the 16th century and many branches had usurped for the throne and or were taken into slavery or murdered..
Antonia Sanctu of Ghargur, Princess of Ethiopia, (1508 – 1568), mistress to Corsair Nicola Sayd of Birgu, Zebbug and of Santi (d. 1536), with issue.
After Nicola Sayd’s death, Antonia remain unattached and a loyal servant to the local Church and to her family. This was one condition that if she were to marry, she and her family would lose their income from the Sayd family. Paid till the death of Antonia in 1568 which by that stage, the family were self supported and independant and free in Society. Even though Antonia was once a Princess, her status in Malta was always based on being a slave then a free-slave [North African or Ethopian royalty or nobility rarely given priviledges in Christandom].
1. Simon Sanctu (1525 -), married to Paola Micallef, with issue.
1.1. Pietro Santu, married 28.6.1567/1569 Birkikara to Isabella Vella.
1.1.1. Giorgio Sant, married 11.9.1605 Gharghur to Vennera Borg.
1.1.1.1. Giuseppe Sant, married 1657 to Antonia Grazia Galea.
1.1.1.2. Michele Sant., married 1618 Matrice Gozo to Innocenza Camilleri.
1.1.2. Margarita Sanctu, married 1597 Matrice, Gozo to Giorgio Sanctu.
2. Fra Salvo Sanctu (1526 -), a Monk – had natural issues.
2.1. (illegitimate) Francesco “sives Rocco‘ Santu, married Francesca.. with issue.
2.1.1. Domenico Sant, married 9.7.1622 Gharghur to Giulia Grazia Grecg, with issue.
2.1.1.1. Caterina Maruzza Sant, married 1651 Gharghur to Paolo Greg.
2.1.1.1. Mro Francesco Sant, married 11.2.1657 Curmi to Domenica Falzon.
2.1.2. Antonio Sant, married 10.10.1639 Gharghur to Vennera Mifsud.
2.1.2.1. Martina Sant, married 22.6.1659 Gharghur to Domenico Spiteri.
2.1.2.2. Andrea Sant, married 1659 to Grazia Mangion., with issue.
2.1.2.2.1. Salvatore Sant, married 11.4.1739 Porto Salvo to Margherita Gatt.(epx veuf de Maria at Birkikara)
2.2. (illegitimate) Elena Sant, married 18.1.1561 Zebbug ou Naxxar to Domenico Sammut.
2.3. (illegitimate) Giovanna Sant, married 1571 Naxxar to Masi Samut.
2.4. (illegitimate) Blasco Sant, married 9.5.1566 Vittoriosa Birgu to Lena Gauci, with issue.
2.4.1. Martino Sant, married (1) 1594 Birgu to Marietta Lombardo, married (2) 1613 Gharghur to Domenica Agius.
3. Bartolomeo Sanctu (1527 -), married (1) to N., married (2) 1552 Naxxar to Francesca Bezzina, with issue
3.1. (First marriage) Salvo (Salvatore) Sant, (wire Bartolomeo dit Miselmet) married (1) to Caterina N, married (2) 18.7.1560 Naxxar to Catarina Cauchi, with issue.
3.1.1. (First marriage) Blasio Sant, married 1566 Vittoriosa to Luna Gariosi, with issue.
3.1.1.1. Giorgio Sant, maried 1617 (Notary Mario Attard) to Paolina Ciantar, with issue.
3.1.1.1.1. Biagio Blasio Sant, married 1654 Valletta to Domenica Agius, with issue.
3.1.1.1.1.1. Angelo Sant, married 1681 Mdina to Petruzza Zerafa, with issue.
3.1.1.1.1.1.1. Maria Sant, married 1710 (Notary Ignazio Debono) to Nobile Antonio Pace.
3.1.1.1.1.1.2. Gio Maria Sant, married 1708 Mdina to Caterina Schembri.
3.1.1.1.1.1.3. Ignazio Sant, married (1) 1717 Mdina to Anna Maria Bugeja, married (2) 1755 Valletta to Anna Parnis.
3.1.1.2. Margherita Sant, married 1637 to Giovanni Cauchi.
3.1.2. (Second marriage) Mattia (Agata) Sant, married 23.10.1576 Naxxar to Pietro Fenech, (CM 3.11.1575 ; test révoqué 8.7.1622 vv Pietro Fenech).
3.1.3. Angiola Sant, married 20.9.1592 Naxxar to Pietro Tonna
3.1.4. Agostino Sant, married 18.10.1595 at Lia Lija to Marietta Zarb, with issue (Wire Salvo and Catarina)
3.1.4.1. Angelica Sant, married 14.6.1620 Gharghur to Pasquale Bezzina (CM 11.2.1620 Angela dite Angelica)
3.1.4.2. Salvatore Sant, married 7.6.1625 Naxxar to Paola ( Paolina) Tonna, with issue (CM 8.4.1625) (Don 13.2.1667)
3.1.4.2.1. Giovanni Sant Bapt 17.3.1627 Naxxar
3.1.4.2.2. Grazia Sant, Bapt 27.11.1621 married (1) 23.7.1650 Naxxar Gregorio Vella (with Giorgio Borg and not Vella) married (2) CM 30.11.1659 to Gio Maria Zarb
3.1.4.2.3. Gio Luca Sant, Bapt 13.12.1632 Naxxar
3.1.4.2.4. Marietta Sant, Bapt 2.7.1636 Naxxar
3.1.4.2.5. Matteolo Sant, Bapt 21.9.1637 Naxxar
3.1.4.2.6. Luca Sant, married (1) 23.7.1654 Gharghur to Margarita Borg married (2) 14.11.1696 Lia Lija to Maria Borg
3.1.4.2.6.1. Grazia Sant, married 24.8.1677 Gharghur to Giovanni Schembri
3.1.4.2.6.2. Paolina Sant, married 10.6.1690 Gharghur to Geronimo Fenech
3.1.4.2.6.3. Maria Sant, married 25.7.1695 Ghaghur to Gio Maria Sammut
3.1.4.2.7. Andrea Sant, married 2.10.1666 Attard to Matteola Attard, with issue
3.1.4.2.7.1. Grazia Sant, married 15.1.1695 Attard to Domenico (dit Domio) Pace
3.1.4.2.7.2 Domenico Sant, married (1) 11.10.1705 Mosta Evangelista Dingli (2) 17.7.1721 Mosta Margarita Camilleri
3.1.4.2.7.2.1. Maria Sant, married 16.10.1735 Attard to Lorenzo Grech
3.1.4.2.7.3. Giulio Sant, married 15.11.1705 Zebbug to Maria Pace, with issue.
3.1.4.2.7.3.1. Grazia Sant married 27.6.1733 Attard to Domenico Pace.
3.1.4.2.7.3.2. Giuseppe Sant, married 1735 Qormi to Maria Diacono, with issue.
3.1.4.2.7.3.2.1. Angelo Sant, married (1) 1767 Birkirkara to Caterina Micallef, married (2) 1800 Valletta to Felicita Magro, with issue.
3.1.4.2.7.3.2.1.1. (Second marriage) Maria Sant, married 1815 Valletta to Nobile Giovanni Abela.
3.1.4.2.7.3.3. Giovanna Sant, married 1742 Attard to Domenico Mifsud.
3.1.4.2.7.4. Domenica Sant, married 16.9.1708 Attard Gio Maria Agius
3.1.4.2.7.5. Giovanni Maria Sant, married 10.1.1706 Attard to Grazia Debono, with issue
3.1.4.2.7.5.1. Andrea Sant, married (1) 1727 Attard to Maria Schembri, married (2) 10.2.1732 Attard to Maria Angelica Giuliano, with issue
3.1.4.2.7.5.1.1. (First marriage) Rosa Maria Sant, married 1750 Attard to Salvatore Agius.
3.1.4.2.7.5.1.2. Grazia Sant, married 1767 Attard to Paolo Borg.
3.1.4.2.7.5.1.3. (Second marriage) Francesca Sant, married 12.6.1768 Attard to Giovanni Bellia.
3.1.4.2.7.5.1.4. Rosa Sant, married 1768 Cospicua to Pietro Magro.
3.1.4.2.7.5.1.5. Agata Sant, married 1771 Attard to Francesco Portelli.
3.1.4.2.7.5.2. Anna Sant, married 24.2.1734 Attard to Antonio Gauci
3.1.4.2.7.5.3. Filippo Sant, married 5.2. 1735 Attard to Caterina Sammut, with issue.
3.1.4.2.7.5.3.1. Maria Sant, married 28.10.1770 Attard to Angelo Saliba.
3.1.4.2.7.5.3.2. Paolina Sant, married 2.7.1776 Attard to Salvatore Buhagiar.
3.1.4.2.7.5.4. Giuseppe Sant, married (1) 28.6.1740 Attard to Grazia Borg, married (2) 21.2.1759 Attard to Maria Pisano.
3.1.4.2.7.5.5. Francesco Sant, married (1) 15.10.1741 Mosta to Celidonia (dite felicita) Sammut, married (2) 30.4.1754 Mosta to Maria Vassallo,. with issue
3.1.4.2.7.5.4.1. (Second marriage) Salvatore Sant, married 1783 to Maria Ebejer.
3.1.4.2.7.5.4.1.1. Francesco Sant, married 1814 to Maria Muscat.
3.1.4.2.7.5.4.2. Giuseppe Sant, married 1786 to Agata Schembri.
3.1.4.2.7.5.4.3. Paolo Sant, married 1799 to Domenica Galea
3.1.4.2.7.5.4.1. Maria Sant, married 21.10.1761 Mosta to Paolo Muscat
3.1.4.2.7.5.4.2. (First Marriage) Giovanni Maria Sant, married 5.10.1766 Mosta to Anna Attard, with issue
3.1.4.2.7.5.4.2.1. Gio Maria Sant, married 1.2.1796 Mosta to Grazia Frendo, with issue
3.1.4.2.7.5.4.2.1.1. Giovanni Maria Sant, married 7.10.1815 Mosta to Anna Sammut.
3.1.4.2.7.5.4.2.1.2. Francesco Sant, married 1857 to Grazia Vella, with issue
3.1.4.2.7.5.4.2.1.3. Caterina Sant, married Francesco Sant.
3.1.4.2.7.5.4.2.2. Francesco Sant, married (1) 29.1.1797 Mosta to Carmela (Cornelia) Frendo, married (2) 13.9.1802 Mosta to Teresa Galea, with issue.
3.1.4.2.7.5.4.2.3. Paolo Sant, married 29.9.1799 Mosta to Paola Vella.
3.1.4.2.7.5.4.2.4. Saverio Sant, married 27.9.1799 Mosta to Anna Frendo, with issue.
3.1.4.2.7.5.4.2.4.1. Paolo Sant, married 12.1.1839 Mosta to Giovanna Sammut, with issue
3.1.4.2.7.5.4.2.4.1.1. Francesco Sant, married 1875 to Caterina Sant-(See Above)
3.1.4.2.7.5.4.2.4.1.1.1. Maria Giuseppina Sant, married Carmelo Deguara.
3.1.4.2.7.5.4.2.4.1.2. Saverio Sant.
3.1.4.2.7.5.4.2.4.1.3. Angelo Sant, married 1897 Mosta to Carmela Muscat, with issue.
3.1.4.2.7.5.4.2.4.1.3.1. Francesco Sant, married 1926 St Paul’s Bay to Carmela Micallef, with issue.
3.1.4.2.7.5.4.2.4.1.3.1.1. Angelo Sant, married to Dolores Muscat, with issue.
3.1.4.2.7.5.4.2.4.1.3.1.1.1. Christopher Sant, married to Teresa Baldacchino, with issue.
3.1.4.2.7.5.4.2.4.1.3.1.1.1.1. Etienne Sant, (1990-), [ancestry]; Engaged to Rachel Schembri dei Conti di Ghajn Tuffieha.
3.1.4.2.7.5.4.2.4.1.4. Carmel Paul Sant
3.1.4.2.7.5.4.2.4.1.5. Anna Sant
3.1.4.2.7.5.4.2.4.1.6. Rosa Sant., married 8.10.1882 Mosta to Carmelo Fenech.
3.1.4.2.7.5.4.2.4.2. Angelo Sant, married 1843 Mosta to Angela Galea, with issue
3.1.4.2.7.5.4.2.4.2.1. Carmelo Sant
3.1.4.2.7.5.4.2.4.2.2. Francesco Saverio Sant, married 1892 to Maria Bezzina, with issue
3.1.4.2.7.5.4.2.4.2.2.1. Albert Sant.
3.1.4.2.7.5.4.2.4.2.2.1.1. Albert Jr. Sant, married to Mary N.
3.1.4.2.7.5.4.2.4.2.2.2. Ann Sant, married to N. Vassallo
3.1.4.2.7.5.4.2.4.2.2.2.1. Philip Vassallo
3.1.4.2.7.5.4.2.4.2.2.3. Nazzareno Sant.
3.1.4.2.7.5.4.2.4.2.2.3.1. Rena Sant, married to N. Aquilina.
3.1.4.2.7.5.4.2.4.2.2.4. George Sant.
3.1.4.2.7.5.4.2.4.2.2.4.1 Maria Sant, married to N. Bodinnar.
3.1.4.2.7.5.4.2.4.2.2.5. Angela Sant, married to N. Vassallo
3.1.4.2.7.5.4.2.4.2.2.5.1. Stephen Vassallo
3.1.4.2.7.5.4.2.4.2.2.6. Teresa Sant, married to N. Muscat, with issue.
3.1.4.2.7.5.4.2.4.2.2.6.1. Pauline Muscat, married to N. Gauci.
3.1.4.2.7.5.4.2.4.2.2.7. Angelo Sant, married to Mary Sammit.
3.1.4.2.7.5.4.2.4.2.2.8. Carmelo Sant, married to Micheline Grech, with issue.
3.1.4.2.7.5.4.2.4.2.2.8.1. Denise Sant.
3.1.4.2.7.5.4.2.4.2.2.8.2. Marie Sant.
3.1.4.2.7.5.4.2.4.2.2.8.3. Xavier Sant, married to Monique Mermet, with issue.
3.1.4.2.7.5.4.2.4.2.2.8.3.1. Stéphane Sant, (1976-, married 2010 to Carine Germaine Gallisa, with issue.
3.1.4.2.7.5.4.2.4.2.2.8.3.1.1. Alexis Xavier Raymond Sant, (2010-.
3.1.4.2.7.5.4.2.4.2.2.8.3.2. Juliette Sant.
3.1.4.2.7.5.4.2.4.2.3. Maria Sant, married 1864 Mosta to Giuseppe Muscat.
3.1.4.2.7.5.4.2.5. Giuseppe Sant, married 9.11.1805 Mosta to Maria Vella, with issue.
3.1.4.2.7.5.4.2.5.1. Paolo Sant, maried 9.6.1847 at Mosta to Grazia Frendo, with issue.
3.1.4.2.7.5.4.2.5.1.1. Carmelo Vincent Paul Sant, First mariage 13.6.1877 at Bône to Rosa Carmela Anna Micallef, Second mariage 5.1.1880 at Tunis to Anna Micallef, with issue.
3.1.4.2.7.5.4.2.5.1.1.1. Paul Sant, (12.3.1878 -7.8.1879 Bône (Algèrie)), d.inf
3.1.4.2.7.5.4.2.5.1.1.2. Joseph Sant, 1881-1929 married 28.4.1908 Bône (Algérie) to Vincente Borg, with issue.
3.1.4.2.7.5.4.2.5.1.1.3. Louis Sant, (1882-1883 Bône (Algérie), d.inf.
3.1.4.2.7.5.4.2.5.1.1.4. Rosine Sant, (1884-1957), married 8.2.1902 Bône (Algérie) to Felix Charles Farrugia.
3.1.4.2.7.5.4.2.5.1.1.5. Louis Sant, 1886-1959 married 14.6.1919 Bône (Algérie) to Helene Catherine Grech.
3.1.4.2.7.5.4.2.5.1.1.6. Pauline Sant, 1889-1941 married 28.9.1909 Bône (Algérie) to Barthelemy Gauci.
3.1.4.2.7.5.4.2.5.1.1.7. Michel Sant, 1892-1894 Bône (Algérie), d.inf.
3.1.4.2.7.5.4.2.5.1.1.8. Michel Ange Sant, 1895-1895 Bône (Algérie), d.inf.
3.1.4.2.7.5.4.2.5.1.1.9. Marie Sant, 1896-1930 Bône (Algérie).
3.1.4.2.7.5.4.2.5.1.1.10. François Jean Sant, 1898-1977 maried 1939 at Bône (Algérie) to Anne Marie Lombardo, with issue.
3.1.4.2.7.5.4.2.5.1.1.10.1. Charles Jérôme Sant, married 1959
3.1.4.2.7.5.4.2.5.1.1.10.2. Gérard Felix Sant, married 1959
3.1.4.2.7.5.4.2.5.1.1.10.3. Geneviève Marie Sant, married 1963
3.1.4.2.7.5.4.2.5.1.1.10.4. Bernard Sant, married 1974
3.1.4.2.8. Domenico Sant, married (1) 2.2.1669 Gharghur to Grazia Grech, Married (2) 29.7.1711 Birkikara to Agata Aquilina (veuf de Lucrezia dite Grazia )
3.1.4.2.8.1. Maria Sant, married 1686 to Nicola Galea
3.1.4.2.8.2. (First Marriage) Agata Sant, married 1698 to Petruccio Cassia
3.1.4.2.8.3. Salvatore Sant, married 20.4.1705 Birkikara to Anna Micallef, with issue.
3.1.4.2.8.3.1. Giacomo Sant, married 1736 Birkirkara to Angelica Zirenzo, with issue.
3.1.4.2.8.3.1.1. Giuseppe Sant, married (1) 1760 Birkirkara to Grazia Grech, married (2) 1767 Attard to Caterina Calafato, with issue.
3.1.4.2.8.3.1.1.1. (First Marriage) Caterina Sant, married 1783 Birkirkara to Maurizo Grech, with issue.
3.1.4.2.8.3.1.1.1.1. Grazia Grech, married 1805 Gharghur to Gio Domenico Portelli.
3.1.4.2.8.3.1.1.2. (Second Marriage) Ignazio Sant, married 1795 Birkirkara to Teresa Cauchi di Cristoforo, with issue.
3.1.4.2.8.3.1.1.2.1. Giacomo Sant, married 1827 Balzan to Maria Dingli, with issue.
3.1.4.2.8.3.1.1.2.1.1. Carmelo Sant, married 1865 Birkirkara to Filomena Muscat, with issue.
3.1.4.2.8.3.1.1.2.1.1.1. Giacomo Sant, married 1887 Birkirkara to Antonia Fenech, with issue.
3.1.4.2.8.3.1.1.2.1.1.1.1. Carmelo Sant, married 1913 Msida to Carmela Bonello, with issue.
3.1.4.2.8.3.1.1.2.1.1.1.1.1. Giuseppe Sant, married 1947 Birkirkara to Josephine Mizzi, with issue.
3.1.4.2.8.3.1.1.2.1.1.1.1.1.1. Dr Alfred Sant, M.Sc., M.B.A., D.B.A. (HARVARD), Prime Minister of Malta (r.1996 – 1998), (1948-., married to Mary Darmanin, with issue.
3.1.4.2.8.3.1.1.2.1.1.1.1.1.1.1. Marta Sant, B.Psych (Hons).
3.1.4.2.8.3.1.1.2.1.1.1.1.1.2. N. Sant, married with issue.
3.1.4.2.8.3.1.1.2.1.1.1.1.1.2.1. Dr Marc Sant LLD.
3.1.4.2.8.3.1.1.2.2. Francesca Sant, married 1817 Birkirkara to Francesco Debono, with issue.
3.1.4.2.8.3.1.1.2.2.1. Maria Debono, married 1842 Valletta to Vincenzo Stafrach.
3.1.4.2.8.3.1.2. Michele Sant, married 1768 Valletta to Vincenza Bugeja, with issue.
3.1.4.2.8.3.1.2.1. Giovanni Sant, married 1802 Valletta to Rosa Abdilla, with issue.
3.1.4.2.8.3.1.2.1.1. Rosaria Sant, married 1835 Valletta to Aloisio Xuereb.
3.1.4.2.8.3.1.2.2. Benuenuta Sant, married 1787 Valletta to Agostino Barbara, Hereditary Nobile of Hungary.
3.1.4.2.8.3.1.2.3. Maria Sant, married 1804 Valletta to Paolo Borg.
3.1.4.2.8.3.1.3. Giovanni Sant, married 1776 Valletta to Maria Muscat, with issue.
3.1.4.2.8.3.1.3.1. Rosalea Sant, married 1801 Valletta to Nicolo Farrugia.
3.1.4.2.8.4. Alberto Sant, married 27.9.1711Mosta to Maria Bartolo, with issue.
3.1.4.2.8.4.1. Grazia Sant, married 1734 Mosta to Nobilis Giuseppe Pace.
3.1.4.3. Pietro Sant, married 3.2.1640 Naxxar to Angelica Vella (sur notaire 1639)
3.1.4.3.1. Maria Sant, married 24.4.1682 Gharghur to Giovanni Portelli. (donation 28.3.1704)
3.1.4.4. Agata Sant, married 20.11.1643 Gharghur to Ambrosio Imbroglia (ou Imbroll) ( test 5.2.1649 ;CM 10.10.1643)
3.1.5. Berta Sant, married 13.1.1603 to Martino Sammut
3.1.6. Giovanni Sant, married 1.1.1605 Gharghur to Elena (dite Luna) Sammut (CM 14.4.1605)
3.1.6.1. Gioanella Sant, married 1623 Gharghur to Lazzaro Grech.
3.1.6.2. Grazia Sant, married 1631 Lorenzo Magro
3.1.6.3. Caterina Sant, married to Andrea Mifsud (their daughter Mattiola married in 1644 to Giovanni Sant).
3.1.6.4. Marietta Sant.
3.2. Biagio Santu, married Luria.., with issue
3.2.1. Giorgio Ambrogio Santu, married 1606 to Gioanella Sammut
3.2.1.1. Pietro Sant, married 1647 to Marualla Xeberras.
3.2.1.1.1. Giuseppe Sant, married 1724 to Grazia Borg.
3.2.1.1.1.1. Maria Sant, married 1776 to Franco Decelis.
3.2.1.1.1.2. Teresa Sant, married 1775 to Niccolo Caruana.
3.2.1.2. Giuseppe Sant, married 1646 to Margherita Xeberras.
3.2.1.3. Domenico Sant, married 19.2.1635 Gharghur to Benedetta Chetcuti, with issue.
3.2.1.3.1. Bernardina Sant, married 1654 to Clement Xerri.
3.2.1.3.2. Giovanni Sant, married 1654 Mosta to Domenica, former wife of Niccolo Vella, with issue.
3.2.1.3.2.1. Domenico Sant, married 16.4.1684 Mosta to Domenica Zammit, with issue.
3.2.1.3.2.1.1. Paolo Sant, married 6.7.1709 Mosta to Maria Pisani.
3.2.1.3.2.1.1.1. Giovanni Sant, married 1.6. 1760 Mosta to Caterina Fenech.
3.2.1.3.2.1.1.1.1. Giuseppe Sant, married 12.10.1794 Mosta to Petra (Pietra ?) Deguara.
3.2.1.3.2.1.1.2. Anna Sant, married 1742 Mosta to Aloisio Zarb.
3.2.1.3.2.1.2. Salvatore Sant, married (1) 1711 to Grazia Grech, married (2) 1740 Mdina to Teresa Sammut, with issue.
3.2.1.3.2.1.2.1. (Second marriage) Grazia Sant, married 1756 Birkirkara to Tomaso Borg.
3.2.1.3.2.1.3. Graziella Sant, married 1724 Mosta to Gio Maria Xerri.
3.2.1.3.2.2. Maria Sant, married 1686 Mosta to Gio Maria Bartolo.
3.2.1.3.2.2.1. Giuseppe Bartolo, married 1707 Valletta to Candita Caruana, with issue.
3.2.1.3.2.2.1.1. Stefano Bartolo, married 1735 Valletta to Angelica Zammit, with issue.
3.2.1.3.2.2.1.1.1. Emmanuele Bartolo, married 1769 Valletta to Ubladesca Grech, with issue.
3.2.1.3.2.2.1.1.1.1. Flippo Bartolo, married 1800 Valletta to Caterina Micallef, with issue.
3.2.1.3.2.2.1.1.1.1.1. Ubladesca Bartolo, married 1819 Valletta to Giuseppe Meli.
3.2.1.3.2.2.1.1.2. Damiano Bartolo, married 1778 Valletta to Dignamerita Sammut, with issue.
3.2.1.3.2.2.1.1.2.1. Maria Anna Bartolo, married 1805 Valletta to Antonio Zammit, with issue.
3.2.1.3.2.2.1.1.2.1.1. Vincenza Zammit, married 1841 Valletta to Paolo Parnis.
3.2.1.3.3. Matteo Sant married 26.6.1654 Curmi Pinto to Grazia Falzon
3.3. (Second Marriage) Dioniso Sant, married 1570 Birkirkara to Paola N, with issue.
3.3.1. Domenico Sant, married 1606 Valletta to Marietta Doneo.
3.3.2. Vincenzo Sant, married to Paola N, with issue.
3.3.2.1. Domenica Sant, married 1623 Naxxar to Leonardo Borg.
3.4. Demetrio Sant, married 1574 Naxxar to Agata Gauci, with issue.
3.4.1. Giorgio Sant, married 1612 Gharghur to Caterina Bezzina, with issue.
3.4.1.1. Pietro Sant, married 1647 Gharghur to Maruzza Xiberras, with issue.
3.4.1.1.1. Giuseppe Sans, married 1696 Balzan to Caterina Borg, with isuse.
3.4.1.1.1.1. Tomaso Sans sives Sant, married 1725 Lija to Maria Agius, with issue.
3.4.1.1.1.1.1. Caterina Sant, married 1755 Lija to Gio Maria Sammut.
3.5. Umberto Sant, married 1580 Birgu to Nobile Rosa Cila, with issue.
4. Desiata Sanctu (1523 -), married Paolo d’Anastasio of Naples and formerly Romania.
5. N. Sanctu, married to Michele d’Anfasino sives Anastasio, with issue.
5.1. Giacoba d’Anfasino, married 1576 to Angelo Ambroglio Gambino.